Ethical handling of fish in ecological research requires anaesthetic methods that are effective, practical, and adaptable for a diversity of field conditions. Estuarine environments, in particular, present challenges due to their fluctuating water chemistry. To improve our understanding of anaesthetic performance for field conditions, we compared AQUI-S, a commonly used clove oil-based anaesthetic, and 2-phenoxyethanol, a cost...

Three new isatin–pyridine-2-oxime hybrids (AM01–03) were synthesized and experimentally evaluated as reactivators of acetylcholinesterase (AChE) inhibited by a surrogate of the nerve agent A-242, in comparison with their 4-oxime isomers previously reported by our research group. Furthermore, the interactions of these molecules within the AChE/A-242 complex were assessed through docking and molecular dynamics (MD) simulations....

Purpose Continuous distillation is widely used in the commodity and petrochemical industry to purify fine chemicals on massive industrial scales; however, this key separation strategy is largely unused within the pharmaceutical industry. This article investigates the development of a pilot-scale continuous distillation system for in-line removal of an excess amine reactant ( i.e. , tert-butylamine) when incorporated within an...

Forest diversity is a multidimensional concept comprising different components such as species diversity, functional diversity, structural diversity and genetic diversity. These diverse elements are recognised as being connected to the health and functioning of forest ecosystems and human well-being. However, information on forest diversity at broad spatial scales is scarce. Thus, the primary goal of this study is to quantify...

World Health Organization (WHO) guidance on the management of cyanobacteria in recreational waters provides a comprehensive framework for reducing human health risks. To provide a global overview of how cyanobacterial risks in recreational waters are managed and to better understand capacity gaps and best practice, we surveyed expert opinion across the world. A total of 161 survey responses were collected from 49 countries. Re...

Mercury (Hg), and specifically methylmercury (MeHg), is a contaminant of global concern to humans and wildlife, but there is still limited understanding of its effects on many taxa. Amphibians are closely associated with water, where Hg is converted to MeHg, and high concentrations of MeHg can reduce survival of amphibians in the wild. However, limited non-lethal proxies exist for estimating MeHg bioaccumulation in amphibian l...