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The performance gap in wetland sustainability: a multicriteria assessment of Zrebar Wetland, IranNARA Subscribed
Assessing the sustainability of stressed wetland ecosystems requires transitioning from reductionist paradigms to frameworks that structurally integrate heterogeneous ecological, socioeconomic, and institutional variables. To bridge the methodological divide between qualitative appraisals and quantitative modeling, this study develops a five-dimensional hierarchical framework and applies the Absolute Measurement Analytic Hiera...
Standardized microhaplotype databases and frameworks for assessing and mining crop genetic diversityNARA Subscribed
Keymessage Standardized microhaplotype databases for eight diverse crops enable multiallelic analyses, comparative genetics, and breeding decisions. Abstract Microhaplotypes are short genomic segments that contain multiple tightly linked variants, providing multi-allelic data that can enhance genetic resolution compared to traditional biallelic single nucleotide polymorphism (SNP) markers. Here, we present the creation and uti...
Effort and substance use: differentiating tobacco use through reinforcement learning of effort based decision makingNARA Subscribed
Effort-based decision making evaluates rewards relative to the effort required to obtain it, an important process of healthy goal-directed motivation and behavior. Computational models provide mechanistic insights underlying choice behavior and potential alterations in neuropsychiatric disorders, including substance use disorders. We applied computational models to effort-based choice behavior to characterize underlying decisi...
In July 2022, a harmful algal bloom of Heterosigma akashiwo originated in a man-made lagoon and expanded to more than 4,500 km² of open-water habitat in the San Francisco Estuary, triggering a widespread mass mortality event involving bony fishes, sharks, rays, crustaceans, mollusks, polychaetes, and jellyfish. Notably, the event affected the southernmost spawning populations of White Sturgeon ( Acipenser transmontanus ) and f...
Continuous Distillation for Drug Substance ManufacturingNARA Subscribed
Purpose Continuous distillation is widely used in the commodity and petrochemical industry to purify fine chemicals on massive industrial scales; however, this key separation strategy is largely unused within the pharmaceutical industry. This article investigates the development of a pilot-scale continuous distillation system for in-line removal of an excess amine reactant ( i.e. , tert-butylamine) when incorporated within an...