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Managing the Unmanageable: Understanding the Competing Effects of Salinity and Nutrient Loading on Estuarine Water QualityNARA Subscribed
Changing climatic conditions that can alter physical characteristics of surface waters may limit the effectiveness of conventional approaches to nutrient management. This study evaluated the competing effects of nutrient loads and changing salinity on chlorophyll-a dynamics in Tampa Bay (Florida, USA). This estuary has demonstrated long-term recovery of water quality primarily through wastewater infrastructure improvements, wh...
Identifying the Drivers of Newfoundland Capelin Recruitment After a Breakdown in the Environment–Recruitment RelationshipNARA Subscribed
Environment‐recruitment relationships often break down over time. This can occur because of spurious results from testing numerous environmental variables in the original analyses or from relative changes in the importance of specific environmental drivers over time. An environment‐recruitment model was developed for the Newfoundland and Labrador capelin stock, but the relationship first weakened with the addition of new data...
Bottom‐tow gear fisheries (trawls and dredges) produce ~24 million mt of harvest annually, representing a globally important animal‐sourced food system. While many are currently sustainably managed, growing concern over the potential for ecosystem impacts from bottom‐tow gears has increased pressure to improve these fisheries. We assembled an international working group of > 30 contributors, including fishing industry particip...
Cyclooxygenase-dependent contribution to increased flow mediated dilatation following a week of repeated ischemic preconditioningNARA Subscribed
Purpose Ischemic preconditioning (IPC) and remote ischemic preconditioning (RIPC) independently enhance endothelial function and flow mediated dilation (FMD); yet the underlying mechanisms remain incompletely defined. This study investigated the contribution of cyclooxygenase (COX) dependent vasodilators to FMD before and after repeated IPC and RIPC. Methods 21 healthy participants underwent Radial artery FMD assessments befor...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
NCBI Orthologs: Public Resource and Scalable Method for Computing High-Precision Orthologs Across Eukaryotic GenomesNARA Subscribed
Orthologs are fundamental for enabling comparative genomics analyses that further our understanding of eukaryotic biology. The unprecedented increase in the availability of high-quality eukaryotic genomes necessitates scalable and accurate methods for orthology inference. The National Center for Biotechnology Information (NCBI) developed “NCBI Orthologs”, a resource and a computational pipeline designed to meet this challenge...
Recombination-aware phylogenomicsNARA Subscribed
Running on empty: capelin diet after stock collapseNARA Subscribed
The Newfoundland capelin stock in Northwest Atlantic Fisheries Organization Divisions 2J3KL collapsed in 1991 with only a modest recovery over 30+ years. Resource limitation is hypothesized to be a driver of this slow stock recovery. Using detailed seasonal diet data (1999–2022), capelin diet was dominated by calanoid copepods in both spring and autumn, with hyperiid amphipods, euphausiids, and appendicularians increasing in i...
Bridging social and ecological science to create spatially explicit models of human-caused mortality of carnivoresNARA Subscribed
Research indicates that human-caused mortality (HCM) is a key factor limiting numerous large carnivore populations. However, efforts to represent HCM in spatially explicit models have generally been limited in scope—often relying on proxies, such as road or human density. Yet such efforts fail to distinguish different sources of HCM, which can arise from different antecedent processes. We offer a systems-based conceptual frame...
Early pyroxene crystallisation deep below mid-ocean ridgesNARA Subscribed
Comparing near-term information from national climate scenarios and initialised decadal predictionsNARA Subscribed
Multi-model decadal predictions and probabilistic climate scenarios are compared and evaluated, using observations from 1961 to 2023. For averages of years 2–9 ahead, initialised predictions show higher skill for Atlantic Multidecadal Variability (AMV) and the winter North Atlantic Oscillation (NAO) but not for global mean surface temperature (GMST). The correlation skill for NAO depends on the composition of the multi-model e...
Stony coral tissue loss disease (SCTLD) has spread throughout Florida’s Coral Reef, causing extensive mortality of over 30 species of reef-building corals, and has rapidly spread to many other countries and territories throughout the Caribbean. Current treatments for SCTLD, including a proprietary paste mixed with the antibiotic amoxicillin, do not provide protection from future infections and may select for antibiotic-resista...
Predicting the progression of MCI and Alzheimer’s disease on structural brain integrity and other features with machine learningNARA Subscribed
Machine learning (ML) on structural MRI data shows high potential for classifying Alzheimer’s disease (AD) progression, but the specific contribution of brain regions, demographics, and proteinopathy remains unclear. Using Alzheimer’s Disease Neuroimaging Initiative (ADNI) data, we applied an extreme gradient-boosting algorithm and SHAP (SHapley Additive exPlanations) values to classify cognitively normal (CN) older adults, th...