The health benefits of soy and soy derived foods are often attributed to their isoflavone (ISFs) content, known to include phytoestrogens. However, EFSA has concluded that there is insufficient scientific evidence to establish a causal relationship between ISFs consumption and the proposed health claims. Although phase-II metabolites of ISFs are often considered as detoxified products with reduced estrogenic effects, recent st...

Climate change is expected to create a range of impacts on biodiversity, land use, and economic activities, but those sector impacts are rarely analysed together. Here, we assess how climate change and socioeconomic narratives will affect land use and biodiversity in the state of Bavaria, Germany. We apply a multi-sectoral modelling approach with two climate projections (RCP 2.6 and 8.5) downscaled from three different climate...

Main conclusion Almond trees prioritize C to yield rather than stem growth, and their overall lower NSC stores compared to forest trees may have consequences for resilience under environmental variability. Abstract Perennial tree crops store nonstructural carbohydrates (NSCs) as energy reserves that can be used to persist during both predictable periods of reduced activity like dormancy and more unpredictable periods associate...

The Asia region harbors exceptional chondrichthyan (shark, ray, and chimaera) diversity but faces intense fishing pressure. The Important Shark and Ray Areas (ISRA) process provides a collaborative, evidence-based framework to identify critical habitats and inform spatial management. We assessed ISRAs across the Bay of Bengal, Southeast Asia, and the Northwest Pacific to characterize their extent, ecological significance, and...

Small-scale aquaculture (SSA) has been promoted as a “blue transformation” strategy to achieve sustainable development. However, it remains unclear how these initiatives contribute to transforming gender relations in coastal communities. This study examines the case of Caleta Buena (Chile), where an SSA project is being implemented with the technical support of researchers. A qualitative methodology was employed using semi-str...

Volcanic lateral collapses represent major hazards through associated eruptive activity, landslide inundation and, in island or coastal settings, the generation of tsunamis. Forecasting the timing, precursory indicators, and magnitude of lateral collapses still remains a significant gap in volcanic risk management, a challenge exemplified by the 2018 lateral collapse of Anak Krakatau, Indonesia. The volcano’s southwestern flan...

Lifestyle-related factors may affect cognition and increase the risk of developing dementia. However, the neurobiological mechanisms underlying the effect of lifestyle-related factors on the brain are not yet fully understood. Myelin, a vital element of brain health, has previously been shown to be involved in dementia-related cognitive decline. However, whether it plays a role in the relation between lifestyle-related factors...

N 2 O emissions by nitrifiers are often estimated using selective inhibitors, such as 1‐alkynes. However, the effects of these inhibitors on anaerobic ammonium‐oxidising (anammox) bacteria are largely unknown. In this study, we assessed the inhibitory effect of linear and aromatic alkynes on anammox activity and identified their target enzyme. ‘ Candidatus Kuenenia stuttgartiensis’ biomass and constructed wetland soil samples...

Pertussis, also known as whooping cough, is a highly infectious respiratory disease caused by the bacterium Bordetella pertussis . The bacterial virulence factor, pertussis toxin (PT), is associated with the manifestation of the characteristic symptoms of pertussis and the severe form of this disease. Increasing case numbers and the lack of treatment options highlight the need to develop novel pharmacological strategies, e.g.,...