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Journal of Molecular Neuroscience · 2025 · Vol. 75 · Issue 2 · Springer
Traumatic brain injury (TBI) remains a major global health challenge with a need for improved diagnostic and prognostic biomarkers. This study aimed to evaluate the biomarker potential of extracellular vesicle (EV)-encapsulated glial fibrillary acidic protein (EV-GFAP), neurofilament light chain (EV-NfL), total tau (EV-T-Tau), and ubiquitin carboxy-terminal hydrolase L1 (EV-UCH-L1) in TBI. A cohort of 93 trauma patients (75 wi...