Biodiversity loss threatens forest ecosystem stability and functioning, while measures to enhance biodiversity trade-off with economic performance. Native tree-species mixtures are promoted to support associated taxa but usually underperform economically compared to non-native species, both in pure and admixed stands. Quantifying ecological–economic trade-offs remains challenging due to uncertainties in economic and biodiversi...

Adaptation to siliceous versus carbonate substrates is thought to be an important driver of speciation in the alpine flora. The role of the pollination system in the formation and maintenance of such species is presently unclear. Here, we chose three species pairs in the genera Gentiana , Primula , and Rhododendron which often occur in geographic proximity or even sympatry to study the existence of pollination barriers in thes...

Purpose of Review We review how ‘abrupt thaw’ has been used in published studies, compare these definitions to abrupt processes in other Earth science disciplines, and provide a definitive framework for how abrupt thaw should be used in the context of permafrost science. Recent Findings We address several aspects of permafrost systems necessary for abrupt thaw to occur and propose a framework for classifying permafrost process...

The Pannonian-Carpathian-Alpine Seismic Experiment (PACASE) is a collaborative project based on a large, passive seismic network comprising 214 temporary stations. Among the primary aims are the imaging of the Earth’s crustal, lithospheric and upper mantle structure, including joint inversions; monitoring and mapping of seismic activity; and interpretation of the data from seismotectonic and geodynamic perspectives. The base o...

Functional traits offer a rich quantitative framework for developing and testing theories in evolutionary biology, ecology and ecosystem science. However, the potential of functional traits to drive theoretical advances and refine models of global change can only be fully realised when species‐level information is complete. Here we present the AVONET dataset containing comprehensive functional trait data for all birds, includi...

Renal interstitial fibrosis is characterized by the development of myofibroblasts, originating from resident renal and immigrating cells. Myofibroblast formation and extracellular matrix production during kidney damage are triggered by various factors. Among these, endothelins have been discussed as potential modulators of renal fibrosis. Utilizing mouse models of adenine nephropathy (AN) and unilateral ureter occlusion (UUO),...

Pathogenic variants in the WDR45 (OMIM: 300,526) gene on chromosome Xp11 are the genetic cause of a rare neurological disorder characterized by increased iron deposition in the basal ganglia. As WDR45 encodes a beta-propeller scaffold protein with a putative role in autophagy, the disease has been named Beta-Propeller Protein-Associated Neurodegeneration (BPAN). BPAN represents one of the four most common forms of Neurodegener...

Located in the critical 1p36 microdeletion region, the chromodomain helicase DNA-binding protein 5 ( CHD5 ) gene encodes a subunit of the nucleosome remodeling and deacetylation (NuRD) complex required for neuronal development. Pathogenic variants in six of nine chromodomain (CHD) genes cause autosomal dominant neurodevelopmental disorders, while CHD5 -related disorders are still unknown. Thanks to GeneMatcher and internationa...

The collaborative cross (CC) is a large panel of mouse-inbred lines derived from eight founder strains (NOD/ShiLtJ, NZO/HILtJ, A/J, C57BL/6J, 129S1/SvImJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ). Here, we performed a comprehensive and comparative phenotyping screening to identify phenotypic differences and similarities between the eight founder strains. In total, more than 300 parameters including allergy, behavior, cardiovascular, cl...