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Probabilistic analysis of tumor growth inhibition models to Support trial designNARA Subscribed
Journal of Theoretical Biology · 2024 · Vol. 595 · Academic Press
Marcus Baaz; Tim Cardilin; Torbjörn Lundh; Mats Jirstrand
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Exposure-response modeling improves selection of radiation and radiosensitizer combinationsNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2022 · Vol. 49 · Issue 2 · Springer
Tim Cardilin; Joachim Almquist; Mats Jirstrand; Astrid Zimmermann; Floriane Lignet; Samer El Bawab; Johan Gabrielsson
A central question in drug discovery is how to select drug candidates from a large number of available compounds. This analysis presents a model-based approach for comparing and ranking combinations of radiation and radiosensitizers. The approach is quantitative and based on the previously-derived Tumor Static Exposure (TSE) concept. Combinations of radiation and radiosensitizers are evaluated based on their ability to induce...
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Erratum to: Tumor Static Concentration Curves in Combination TherapyNARA Subscribed
The AAPS Journal · 2017 · Vol. 19 · Issue 2 · Springer
Tim Cardilin; Joachim Almquist; Mats Jirstand; Alexandre Soselly; Christiane Amendt; Samer El Bawab; Johan Gabrielsson
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Tumor Static Concentration Curves in Combination TherapyNARA Subscribed
The AAPS Journal · 2017 · Vol. 19 · Issue 2 · Springer
Tim Cardilin; Joachim Almquist; Mats Jirstrand; Alexandre Sostelly; Christiane Amendt; Samer El Bawab; Johan Gabrielsson
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