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Polarisation is a key process in land systems, describing land-change trajectories within a region that simultaneously move in opposite directions, such as co-occurring agricultural intensification and abandonment. Land-system polarisation relates strongly to sustainability goals, with potentially positive or negative consequences depending on domain and context. Yet, we lack approaches for mapping polarisation, limiting our u...
Marine sterols from brown seaweeds, particularly fucosterol and its oxidized derivative saringosterol, have shown therapeutic potential for Alzheimer’s disease (AD) and cardiovascular diseases. Here, we aimed to elucidate the cellular and in vivo mechanisms underlying their beneficial effects. In human HepG2 hepatocytes and CCF-STTG1 astrocytoma cells, we assessed liver x receptor (LXRα /LXRβ) activation, sterol uptake, and ef...