Timothy Bruce results 96
· Newest (Page 1/4, per page 25)
Author: Timothy Bruce ×Clear All Filters
Search Results
Efficacy of an Inactivated Bacterin Vaccine Against Emerging Streptococcus dysgalactiae in Channel Catfish ( Ictalurus punctatus )NARA Subscribed
Lancefield Group C Streptococcus dysgalactiae recently emerged as a catfish pathogen in the US. Reports from hatcheries suggest S. dysgalactiae causes substantial broodfish loss. We aimed to develop a challenge model and evaluate vaccine efficacy against S. dysgalactiae in juvenile channel catfish ( Ictalurus punctatus ). Three S. dysgalactiae (14–1, 14–24 and 14–25) isolates were tested for virulence. Intracoelomic (IC) injec...
Pacific white shrimp ( Litopenaeus vannamei ) are among the most important aquaculture species but are highly susceptible to Vibrio infections. Novel disease management strategies are necessary. Previous studies have reported that peracetic acid (PAA) is an effective disinfectant, but its application in shrimp aquaculture remains underexplored. This study aimed to determine the median lethal concentration (LC 50 ) of PAA at tw...
Shrimp aquaculture is a rapidly expanding food sector; however, its sustainability is challenged by disease outbreaks often linked to imbalances in the microbiome. Here, we characterized the microbial communities in the intestines of shrimp and pond water from three Egyptian farms (A, B, and C) using Oxford Nanopore long-read sequencing. Descriptive comparisons of relative abundance and diversity trends revealed that pond wate...
Interlaboratory clinical chemistry parameter variation in seven-day acute hydrazine toxicity studies in the Sprague-Dawley ratNARA Subscribed
Clinical chemistry retains its position as a cornerstone of toxicological assessment, yet inter-laboratory variability in baseline values remains a challenge for the integration and interpretation of multisite datasets. This study leveraged a publicly available clinical chemistry database to assess the impact of inter-laboratory variability in response to hydrazine-induced steatosis. Seventeen clinical chemistry and physico-ch...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
Comparison and efficacy of soy-based ingredients in practical diets for Florida pompano (Trachinotus carolinus)NARA Subscribed
Three Trials were performed to understand better how soy processed in different ways impacts the growth, feed conversion ratio, and health of the Florida pompano ( Trachinotus carolinus ). The first two growth Trials were performed to evaluate the efficacy of an open soy-based diet compared to a commercially produced, fish meal (FM)–based diet. Trial 1 compared a soy-based diet to a commercial FM-based diet using juvenile fish...
An Overview of Vaccine Development Strategies for Columnaris‐Causing Bacteria in Cultured FishNARA Subscribed
Columnaris disease, caused by columnaris‐causing bacteria (CCB), affects cultured and wild freshwater fish worldwide. Belonging to the phylum Bacteroidota and the family Flavobacteriaceae, CCB are gram‐negative, yellow‐pigmented bacteria that are presumed ubiquitous in freshwater habitats. Since the first report of the disease in 1922, growth and survival, pathogenesis, and transmission of these pathogens have been intensely r...
Flavobacterium covae and virulent Aeromonas hydrophila are prevalent bacterial pathogens within the US catfish industry that can cause high mortality in production ponds. An assessment of in vivo bacterial coinfection with virulent A. hydrophila (ML09‐119) and F. covae (ALG‐00‐530) was conducted in juvenile channel catfish ( Ictalurus punctatus ). Catfish were divided into seven treatments: (1) mock control; (2) and (3) high a...
Many bacterial pathogens impact the US catfish industry, and disease control can be challenging for producers. Columnaris disease in channel catfish, Ictalurus punctatus , is primarily caused by Flavobacterium covae (formerly F. columnare ). Immunostimulants may enhance nonspecific immune responses and offer an alternative to antibiotic treatments in catfish. Furthermore, dietary protein sources and inclusions are also essenti...
The Consortium for Metabonomic Toxicology (COMET) studies was designed to model metabolic responses to organ- and mechanism-specific toxins to predict acute drug toxicity in rats. A range of clinical chemical parameters were measured in 7-day toxicology studies for 86 toxins eliciting a range of organ- and mechanism-specific effects. Additionally, 21 surgical or physiological stressors were evaluated to identify physiological...