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The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
Motivation Here, we make available a second version of the BioTIME database, which compiles records of abundance estimates for species in sample events of ecological assemblages through time. The updated version expands version 1.0 of the database by doubling the number of studies and includes substantial additional curation to the taxonomic accuracy of the records, as well as the metadata. Moreover, we now provide an R packag...
The Toxicology Investigators Consortium 2023 Annual ReportNARA Subscribed
Purpose of Review Environmental chemical exposures may disrupt child development, with long-lasting health impacts. To date, U.S. studies of early environmental exposures have been limited in size and diversity, hindering power and generalizability. With harmonized data from over 60,000 participants representing 69 pregnancy cohorts, the National Institutes of Health’s Environmental influences on Child Health Outcomes (ECHO) P...
Carbonservation with Demonstrated Biodiversity and Carbon Gains: Carbon Can Pay But Biodiversity Must LeadNARA Subscribed
Land use has a critical role to play in both climate change mitigation and biodiversity conservation, and increasingly there have been calls to integrate policies for concurrently meeting Paris Agreement commitments and the UN decade on ecosystem restoration 2021–2030. Currently however, investment activities have been dominated by climate change mitigation activities, including through the development of carbon markets (both...
Collaborative fisheries research programs engage stakeholders in data collection efforts, often with the benefit of increasing transparency about the status and management of natural resources. These programs are particularly important in marine systems, where management of recreational and commercial fisheries have historically been contentious. One such program is the California Collaborative Fisheries Research Program (CCFR...
Metergoline Shares Properties with Atypical Antipsychotic Drugs Identified by Gene Expression Signature ScreenNARA Subscribed
Novel approaches are required to find new treatments for schizophrenia and other neuropsychiatric disorders. This study utilised a combination of in vitro transcriptomics and in silico analysis with the BROAD Institute’s Connectivity Map to identify drugs that can be repurposed to treat psychiatric disorders. Human neuronal (NT2-N) cells were treated with a combination of atypical antipsychotic drugs commonly used to treat psy...
The Toxicology Investigators Consortium 2022 Annual ReportNARA Subscribed
Current carbon prices do not stack up to much land use change, despite bundled ecosystem service co‐benefitsNARA Subscribed
Biological sources of carbon sequestration such as revegetation have been highlighted as important avenues to combat climate change and meet global targets by the global community including the Paris Climate Agreement. However, current and projected carbon prices present a considerable barrier to broad‐scale adoption of tree planting as a key mitigation strategy. One avenue to provide additional economic and environmental ince...
Polyploidy in creosote bush ( Larrea tridentata ) shapes the biogeography of specialist herbivoresNARA Subscribed
Aim Whole‐genome duplication (polyploidy) can influence the biogeography and ecology of plants that differ in ploidy level (cytotype). Here, we address how two consequences of plant polyploidy (parapatry of cytotypes and altered species interactions) shape the biogeography of herbivorous insects. Location Warm deserts of North America. Taxa Gall midges ( Asphondylia auripila group, Diptera: Cecidomyiidae) that attack three par...