Timothy D. Mitchell results 16
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Thermal history and behavioural plasticity shape reef fish tolerance to marine heatwavesNARA Subscribed
Marine heatwaves are becoming more frequent and intense, driving mass fish mortalities and reshaping marine ecosystems, yet the capacity of fishes to tolerate heatwaves remains unclear. We quantified physiological condition and behavioural responses of juvenile warm-water ( Abudefduf vaigiensis ) and cool-water ( Microcanthus strigatus ) fishes from three natural climate analogues—an ambient temperate reef, an ocean warming an...
Peripheral microRNA signature in genetic frontotemporal dementia—findings from the GENFI initiativeNARA Subscribed
Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by significant clinical and genetic heterogeneity, with approximately 40% of cases linked to hereditary genetic mutations, including MAPT , GRN , and C9ORF72 . Recently, microRNAs (miRNAs) have emerged as key regulators of cellular processes related to neurodegeneration and as potential biomarkers for FTD. However, their relevance in presymptomatic stag...
Extreme climatic events and gradual climate change are increasingly anticipated to interact and reshape ecological communities. However, the combined effects of ocean warming, acidification and marine heatwaves on host‐associated microbial communities and their potential role in host adaptation remain poorly understood. Here, we assessed shifts in gut microbiome communities and their associations with physiological performance...
Range‐extending fish become competitive dominants under ocean warming but not heatwaves or acidificationNARA Subscribed
Ocean warming is driving species range extensions into cooler regions. The direct physiological influence of warming on species performance can accelerate such extensions into novel ecosystems; however, indirect effects of invader–resident interactions in cooler regions may counter these positive effects. Here, we examined the foraging performance and densities of competing warm‐water and cool‐water fishes across a latitudinal...
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
Crowdsourced observation networks are typically much more dense than those maintained by National Meteorological Services, and sample a much wider range of local climates. This offers an opportunity to build observed climatologies that are more representative of lived experience, particularly in cities. This study provides a worked example to show their potential for improving operational climate services, and to identify the...
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