Tuberculosis (TB) treatment is highly effective, but response to therapy varies by geography and population subgroups. We assessed differences in TB treatment response in a representative and heterogeneous Brazilian population. We estimated genetic ancestry according to major genetic ancestry groups (African, European, and Amerindian) in the Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil cohort usi...

Marine heatwaves are becoming more frequent and intense, driving mass fish mortalities and reshaping marine ecosystems, yet the capacity of fishes to tolerate heatwaves remains unclear. We quantified physiological condition and behavioural responses of juvenile warm-water ( Abudefduf vaigiensis ) and cool-water ( Microcanthus strigatus ) fishes from three natural climate analogues—an ambient temperate reef, an ocean warming an...

Pacific white shrimp ( Litopenaeus vannamei ) are among the most important aquaculture species but are highly susceptible to Vibrio infections. Novel disease management strategies are necessary. Previous studies have reported that peracetic acid (PAA) is an effective disinfectant, but its application in shrimp aquaculture remains underexplored. This study aimed to determine the median lethal concentration (LC 50 ) of PAA at tw...

Aims Root exudates play a central role in rhizosphere processes, many of which support plant growth. While increased exudation under abiotic stresses has been frequently linked to enhanced plant resilience, crop- and genotype- and soil-specific exudation patterns under non-stress conditions remain poorly understood. This study aimed to assess how soil type and genotype influence root exudation in major and emerging European cr...

Artificial Intelligence (AI) is increasingly influencing chemical risk assessment, enabling faster, more comprehensive, and potentially more ethical assessments. The application of AI in chemical risk assessment refers to both generative and predictive algorithms encompassing machine learning, to analyse complex chemical, biological, and environmental data and provide insights into adverse effect potential for humans and ecosy...

We demonstrate that the inputs and conceptual foundation needed for individual-tree-level precision thinning optimization algorithms are already available. As more resource managers adopt LiDAR-based inventories, precision thinning can become a value-added outcome of collecting these data. We use LiDAR to assess individual-tree stem volumes in Pinus taeda L. plantations in the southeast US. Rather than arbitrarily selecting st...

Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by significant clinical and genetic heterogeneity, with approximately 40% of cases linked to hereditary genetic mutations, including MAPT , GRN , and C9ORF72 . Recently, microRNAs (miRNAs) have emerged as key regulators of cellular processes related to neurodegeneration and as potential biomarkers for FTD. However, their relevance in presymptomatic stag...

The oceanward surface transport of particles, including marine litter, from the northwestern African upwelling zone is influenced by multiple interacting physical processes. This study applies the OceanParcels Lagrangian framework to investigate the mechanisms that may contribute to oceanward surface transport in this region, motivated by the hypothesis that the northwestern African upwelling system could represent a potential...