Entanglement is one of the primary anthropogenic threats to the North Atlantic right whale ( Eubalaena glacialis ; right whale) whose habitat overlaps fixed-gear fishing grounds in the Northwest Atlantic with entanglements representing around half of the mortality and serious injury incidents. Right whale mortality has reached levels that require intervention under the Marine Mammal Protection Act, creating the need for a tool...

Irritable bowel syndrome (IBS) is a gut-brain disorder of multifactorial origin. Evidence of disturbed serotonergic function in IBS accumulated for the 5-HT 3 receptor family. 5-HT 3 Rs are encoded by HTR3 genes and control GI function, and peristalsis and secretion, in particular. Moreover, 5-HT 3 R antagonists are beneficial in the treatment of diarrhea predominant IBS (IBS-D). We previously reported on functionally relevant...