Timothy Phillips results 119
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Rationale A major obstacle in the pre-clinical study of mood-related disorders and novel affective state therapeutic evaluation is the lack of animal models that fully recapitulate human symptomatology. Objective In this study, we developed a touchscreen-based cognitive judgement bias (CJB) task for mice. Methods In the CJB task, animals first learned to discriminate between two visual stimuli displayed on the touchscreen: one...
Individual Trees Respond to 40 Years of Climate Change Through Leaf Functional Trait AcclimationNARA Subscribed
Forests are vital for regulating climate and sustaining biodiversity, but climate change threatens their ability to do so, especially in the tropics. Our knowledge of how tropical forests and their constituent trees will respond to changes in climate is largely based on functional trait studies; however, few previous studies have investigated trait changes within individual tropical trees across decades, limiting our ability t...
Timing Is Everything: The Effect of Exposure to Pollution on Wildlife Gut Microbiota Is Contingent on SeasonNARA Subscribed
Exposure to environmental pollutants can disrupt the gut microbiota, but how pollutants impact natural, seasonal changes in wildlife gut microbiota remains unknown. We quantified how exposure to radionuclides affected temporal changes in the gut microbiota of bank voles ( Clethrionomys glareolus ) inhabiting the Chornobyl Exclusion Zone (CEZ), Ukraine. Wild‐caught bank voles from contaminated and uncontaminated areas within th...
Distribution and ecology of the four Macrourus species by‐caught in the longline fishery at South Georgia, Southern OceanNARA Subscribed
Although Macrourus species are the main by‐catch across Southern Ocean longline fisheries, including around South Georgia, the lack of species‐specific data has hindered effective management and ecological understanding. Aggregation of macrourids at genus level masks critical interspecific differences in life‐history strategies and vulnerabilities to fishing. Here, we provide the first comprehensive biological assessment of th...
Adsorption and detoxification of poly- and perfluoroalkyl substances (PFAS) with hydrophobic bentonite claysNARA Subscribed
PFAS is a class of emerging contaminants, and their exposure has been linked to many deleterious health effects which pose major threats to public health. Dietary intake has been recognized as the principal source of PFAS exposure to animals and humans while drinking water is the major route. Given the persistent nature of PFAS in water and the environment, this study was designed to provide effective and potentially scalable...
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
When the first transoceanic telegraph cables were laid in the mid-1800s, rapid communication between continents became possible. The advent of fibre-optic submarine cables in the 1990s catalyzed a global digital revolution. Today, a network of > 1.7 million kilometres of fibre-optic cables crosses the oceans, carrying more than 99% of all digital data traffic worldwide and trillions of dollars in financial transactions. These...
Exposure of animals and humans to PFAS through contaminated water and foods pose significant threats to public health. To tackle this challenge, this study aimed to develop edible clays that might enhance the binding, detoxification, and elimination of PFAS in the gastrointestinal tract. Montmorillonite clays (CM) were amended with caffeine (CMCAF), curcumin (CMCUR), and riboflavin (CMRIB), and the binding efficacy for a mixtu...
Like many forage fish species, Pacific sand lance ( Ammodytes personatus ) play a key role in nearshore marine ecosystems as an important prey source for a diverse array of predators in the northeastern Pacific. However, the primary threats to Pacific sand lance and their habitat are poorly defined due to a lack of systematic data. Crucial information needed to assess their population status is also lacking including basic kno...
The Toxicology Investigators Consortium 2023 Annual ReportNARA Subscribed
Dominance and rarity in tree communities across the globe: Patterns, predictors and threatsNARA Subscribed
Aim Ecological and anthropogenic factors shift the abundances of dominant and rare tree species within local forest communities, thus affecting species composition and ecosystem functioning. To inform forest and conservation management it is important to understand the drivers of dominance and rarity in local tree communities. We answer the following research questions: (1) What are the patterns of dominance and rarity in tree...
Geography and ecology shape the phylogenetic composition of Amazonian tree communitiesNARA Subscribed
Aim Amazonia hosts more tree species from numerous evolutionary lineages, both young and ancient, than any other biogeographic region. Previous studies have shown that tree lineages colonized multiple edaphic environments and dispersed widely across Amazonia, leading to a hypothesis, which we test, that lineages should not be strongly associated with either geographic regions or edaphic forest types. Location Amazonia. Taxon A...