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Hypertrophic cardiomyopathy (HCM) has long been viewed as the archetypal monogenic disorder caused by pathogenic variants in the genes encoding components of the sarcomere. However, the fact that only one-third of HCM cases are genotype-positive, as well as other factors such as incomplete disease penetrance and marked phenotypic heterogeneity, challenge this reductionist view. Recent advances in mass spectrometry-based proteo...
Precision Forestry: Using Machine Learning and LiDAR to Inform Thinning in Pinus taeda Plantations – A Case StudyNARA Subscribed
We demonstrate that the inputs and conceptual foundation needed for individual-tree-level precision thinning optimization algorithms are already available. As more resource managers adopt LiDAR-based inventories, precision thinning can become a value-added outcome of collecting these data. We use LiDAR to assess individual-tree stem volumes in Pinus taeda L. plantations in the southeast US. Rather than arbitrarily selecting st...
Future temperature-related mortality in various climate change and adaptation scenarios in FinlandNARA Subscribed
Human mortality rates are known to be related to ambient temperature and are expected to be affected by climate change. We applied a distributed lag non-linear model (DLNM) to determine regional temperature-mortality relationships in 19 out of 23 Finnish wellbeing service counties, based on daily death and temperature data from the period 2000–2017. We estimated future heat- and cold-related mortality during this century using...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
Socioeconomic narratives for future healthcare and social welfare in Finland to inform climate change adaptationNARA Subscribed
We present a seven-step method to co-produce, with stakeholders, four narrative extensions of the global shared socioeconomic pathways (SSPs) for the Finnish healthcare and social welfare sector. These are based on an iterative process centred around a workshop attended by approximately 40 participants offering a range of sectoral perspectives. Using general background global- and European-scale descriptions of the SSPs, works...
Calcium (Ca) is a critical plant nutrient typically applied at the time of planting in intensive Eucalyptus plantations in South America. At two sites in Colombia, we examined (1) calcium source by comparing growth after application of 100 kg ha−1 elemental Ca as lime or as pelletized highly reactive calcium fertilizer (HRCF) compared to a no application control, and (2) Ca rate by applying 0, 100, 200, and 400 kg ha−1 element...
Financial Returns for Biomass on Short-Rotation Loblolly Pine Plantations in the Southeastern United StatesNARA Subscribed
Rising demand for renewable energy has created a potential market for biomass from short-rotation pine plantations in the southeastern United States. Site preparation, competition control, fertilization, and enhanced seedling genotypes offer the landowner several variables for managing productivity, but their combined effects on financial returns are unclear. This study estimated returns from a hypothetical 10-year biomass har...
Shared socioeconomic pathways for climate change research in Finland: co-developing extended SSP narratives for agricultureNARA Subscribed
Shared socioeconomic pathways (SSPs), developed at global scale, comprise narrative descriptions and quantifications of future world developments that are intended for climate change scenario analysis. However, their extension to national and regional scales can be challenging. Here, we present SSP narratives co-developed with stakeholders for the agriculture and food sector in Finland. These are derived from intensive discuss...
A 50-Year Retrospective of the Forest Productivity Cooperative in the Southeastern United States: Regionwide TrialsNARA Subscribed
In 2019, the Forest Productivity Cooperative (FPC) celebrated its 50th anniversary. The mission of the FPC is and has been creating innovative solutions to enhance forest productivity and value through the sustainable management of site resources. This industry-government-university partnership has generated seminal research with sweeping implications for increasing productivity throughout the southeastern United States and La...