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Deviations from additivity in APOE4-mediated late-onset Alzheimer’s disease risk across races and ethnicitiesNARA Subscribed
APOE ’s ε4 haplotype ( APOE4 ) is late onset Alzheimer’s disease’s (LOAD) strongest genetic risk factor. Therefore, accurately modeling APOE4 ’s effect is critical to understanding LOAD. This is especially important as APOE4 odds ratios (OR) vary across racial and ethnic (R/E) groups. We analyzed the APOE4 -LOAD association in 3,196 East Asian, 31,105 non-Hispanic White (White), 1,646 Hispanic and Latino (Hispanic), and 6,068...
Climate Attribution in Fishery Stock Assessment: Case Studies From the Northeast U.S. Groundfish StocksNARA Subscribed
Climate change poses an unprecedented risk to fisheries ecosystems and economies globally. Ocean warming has led to observed geographic shifts and changes in the productivity of fish stocks. Due to the rapid pace of change in many of the world's oceans, there is a critical need to develop and apply scientific knowledge and tools that can help account for non‐stationarity and integrate climate and ecosystem drivers into fishery...
Ecosystem metabolism (e.g., gross primary production [GPP], respiration [R], and net ecosystem production) integrates the activity of aerobic organisms and is an indicator of environmental change. Microplastics (i.e., particles 1–5 mm) are widespread in freshwater ecosystems and are colonized by biofilms and other organisms. However, microplastics' effects on ecosystem‐level processes including metabolism or other gas fluxes i...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
Blowing the trumpet for fungal conservation: a comprehensive assessment of the conservation status of Cantharellus and CraterellusNARA Subscribed
There is a growing appreciation of the role that fungi play in ecosystems, and thus their importance in conservation efforts. However, they remain under-represented and very few species have had their conservation status assessed at a global level. In this study we looked at a well-known group of fungi, the chanterelles of Cantharellus and Craterellus and evaluated the extinction risk of this group using the IUCN Red List meth...
Pedigree‐Informed Abundance Estimation for the Endangered North Atlantic Right Whale ( Eubalaena glacialis ) via Gametic Mark‐RecaptureNARA Subscribed
Pedigrees can provide important data for abundance estimation by providing a means to infer the presence of individuals that might otherwise not be detected. Such information may be particularly important for endangered species, where the addition or removal of just a few individuals can make the difference between population growth and decline. Here, we use gametic mark‐recapture methods to incorporate pedigree information in...
Climate change is expected to have significant impacts on the biology, abundance and distribution of transboundary fish stocks, not only among neighbouring countries within the jurisdictions of regional fisheries management organisations (RFMOs) but also between adjacent RFMOs. Using South Pacific albacore tuna ( Thunnus alalunga ) as a case study, we highlight how RFMOs need to understand the impacts of climate change on tran...
Species reordering increases community variability driven by chronic nutrient additionNARA Subscribed
Reordering of abundances among species is a common response in communities whether affected by anthropogenic drivers or natural disturbance. However, understanding how competitive relationships drive community dynamics under global environmental change remains limited, primarily due to uncertainties related to changes in species interactions and the scarcity of long‐term observations. By combining long‐term data and time serie...
The role of dominant species in community organization and aboveground production in semiarid grasslandsNARA Subscribed
Dominant species play a key role in plant communities, influencing the abundance and richness of subordinate species through competitive and facilitative interactions. However, generalizations about the effects of dominant plant species in grasslands can be difficult due to the many differences among communities, such as abiotic conditions and regional species pools. To overcome this issue, we conducted a dominant species remo...
Motivation Here, we make available a second version of the BioTIME database, which compiles records of abundance estimates for species in sample events of ecological assemblages through time. The updated version expands version 1.0 of the database by doubling the number of studies and includes substantial additional curation to the taxonomic accuracy of the records, as well as the metadata. Moreover, we now provide an R packag...
Adaptive sampling with PIXL on the Mars Perseverance roverNARA Subscribed
The Australian lungfish, Neoceratodus forsteri, is one of the world’s oldest vertebrate lineages, with a slow life-history and threatened status, requiring immediate conservation efforts. The main threats to lungfish populations are degradation and availability of key macrophyte habitats, water regulation and flow modification. As this long-lived species (at least 77 years) has delayed maturity (mature at 10 years), field moni...