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Along the U.S. east coast, the widespread non-native red alga Gracilaria vermiculophylla provides habitat for an array of macroinvertebrates, including the eastern mudsnail Ilyanassa obsoleta . Though I. obsoleta tolerates a wide temperature range, increases in summer water temperatures may enhance mortality; furthermore, the presence of non-native algae in rising seawater temperatures could exacerbate harmful conditions. We t...
Like many forage fish species, Pacific sand lance ( Ammodytes personatus ) play a key role in nearshore marine ecosystems as an important prey source for a diverse array of predators in the northeastern Pacific. However, the primary threats to Pacific sand lance and their habitat are poorly defined due to a lack of systematic data. Crucial information needed to assess their population status is also lacking including basic kno...
Purpose of Review Environmental chemical exposures may disrupt child development, with long-lasting health impacts. To date, U.S. studies of early environmental exposures have been limited in size and diversity, hindering power and generalizability. With harmonized data from over 60,000 participants representing 69 pregnancy cohorts, the National Institutes of Health’s Environmental influences on Child Health Outcomes (ECHO) P...
Natural selection on feralization genes contributed to the invasive spread of wild pigs throughout the United StatesNARA Subscribed
Despite a long presence in the contiguous United States (US), the distribution of invasive wild pigs ( Sus scrofa × domesticus ) has expanded rapidly since the 1980s, suggesting a more recent evolutionary shift towards greater invasiveness. Contemporary populations of wild pigs represent exoferal hybrid descendants of domestic pigs and European wild boar, with such hybridization expected to enrich genetic diversity and increas...
Dose selection for aztreonam-avibactam, including adjustments for renal impairment, for Phase IIa and Phase III evaluationNARA Subscribed
Purpose A series of iterative population pharmacokinetic (PK) modeling and probability of target attainment (PTA) analyses based on emerging data supported dose selection for aztreonam-avibactam, an investigational combination antibiotic for serious Gram-negative bacterial infections. Methods Two iterations of PK models built from avibactam data in infected patients and aztreonam data in healthy subjects with “patient-like” as...
Quantifying risks avoided by limiting global warming to 1.5 or 2 °C above pre-industrial levelsNARA Subscribed
The Paris Agreement aims to constrain global warming to ‘well below 2 °C’ and to ‘pursue efforts’ to limit it to 1.5 °C above pre-industrial levels. We quantify global and regional risk-related metrics associated with these levels of warming that capture climate change–related changes in exposure to water scarcity and heat stress, vector-borne disease, coastal and fluvial flooding and projected impacts on agriculture and the e...
Globally, tree fecundity exceeds productivity gradientsNARA Subscribed
Lack of tree fecundity data across climatic gradients precludes the analysis of how seed supply contributes to global variation in forest regeneration and biotic interactions responsible for biodiversity. A global synthesis of raw seedproduction data shows a 250‐fold increase in seed abundance from cold‐dry to warm‐wet climates, driven primarily by a 100‐fold increase in seed production for a given tree size. The modest (three...
Madagascar Terrestrial Camera Survey Database 2021: A collation of protected forest camera surveys from 2007–2021NARA Subscribed
Madagascar is a threatened global biodiversity hotspot and conservation priority, yet we lack broad‐scale surveys to assess biodiversity across space and time. To fill this gap, we collated camera trap surveys, capturing species occurrences within Madagascar into a single standardized database. This data set includes nine distinct protected areas of Madagascar and encompasses 13 subprojects, 38 camera arrays, and 1156 sampling...
Combined effect of alcohol and cannabis on simulated drivingNARA Subscribed
An Evaluation of the Performance of Sea Ice Thickness Forecasts to Support Arctic Marine TransportOA Marine
In response to declining sea ice cover, human activity in the Arctic is increasing, with access to the Arctic Ocean becoming more important for socio-economic reasons. Accurate knowledge of sea ice conditions is therefore becoming increasingly important for reducing the risk and operational cost of human activities in the Arctic. Satellite-based sea ice charting is routinely used for tactical ice management, but the marine sec...
TRY plant trait database – enhanced coverage and open accessNARA Subscribed
Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodivers...
Effects of life history and reproduction on recruitment time lags in reintroductions of rare plantsNARA Subscribed
Reintroductions are important components of conservation and recovery programs for rare plant species, but their long‐term success rates are poorly understood. Previous reviews of plant reintroductions focused on short‐term (e.g., ≤3 years) survival and flowering of founder individuals rather than on benchmarks of intergenerational persistence, such as seedling recruitment. However, short‐term metrics may obscure outcomes beca...
While genetic diversity is hypothesized to be an important factor explaining invasion success, there is no consensus yet on how variation in source populations or demographic processes affects invasiveness. We used mitochondrial DNA haplotypic and microsatellite genotypic data to investigate levels of genetic variation and reconstruct the history of replicate invasions on three continents in a globally invasive bird, the monk...