For a long time, the physiological activity of TRP ion channels and the response to various stimuli have been the focus of attention, and the physiological functions mediated by ion channels have subtle links with the occurrence of various diseases. Our group has been engaged in the study of ion channels. In recent years, the report rate of TRPA1 , the only member of the TRPA subfamily in the newly described TRP channel, has b...

Aim Latitudinal variation in biotic interactions is recognized as a driver underlying variation in plant invasion success and therefore an important issue in conservation biogeography. However, previous studies have mainly focused on interactions between living plants and herbivores, whereas litter traits and detritivory have been hardly studied along latitude or compared between native and invasive plants. Our aim was to comp...

Extracellular ATP is a potent signaling molecule released from various cells throughout the body and is intimately involved in the pathophysiological functions of the nervous system and immune system by activating P2 purinergic receptors. Recent increasingly studies showed that extracellular ATP exhibits circadian oscillation with an approximately 24-h periodicity, which participates in regulatory pathways of central oscillato...

The basic research indicated that microglial P2Y12 receptors ( P2Y12Rs ) are involved in the pathophysiology of epilepsy through regulated microglial-neuronal interactions, aberrant neurogenesis, or immature neuronal projections. However, whether the clinic case of epilepsy would be associated with P2Y12 receptor gene polymorphisms is presented with few data. In our study, a total of 176 patients with epilepsy and 50 healthy c...