Charcot–Marie–Tooth disease (CMT) is the most common inherited peripheral neuropathy, with currently no effective treatment or cure. CMT1A is caused by a duplication of the PMP22 gene, which leads to Schwann cell differentiation defects and dysmyelination of the peripheral nerves. The epigenetic regulator histone deacetylase 3 (HDAC3) has been shown to negatively regulate myelination as well as its associated signaling pathway...

Needle nematodes are polyphagous root-ectoparasites parasitizing a wide range of economically important plants not only by directly feeding on root cells, but also by transmitting nepoviruses. This study deciphers the diversity of the complex Longidorus goodeyi through integrative diagnosis method, based on a combination of morphological, morphometrical, multivariate analysis and molecular data. A new Longidorus species, Longi...

Aims To detect changes in area and vegetation dynamics of monsoon rain forests in relation to disturbance and an observed wetting trend. Location The Mitchell Plateau and the Bougainville Peninsula (north Kimberley, Australia). Methods Geo‐rectified aerial photographs acquired in 1949 and 1969 and a pre‐existing map from 2005 were used to detect changes in rain forest boundaries. To ground‐truth rain forest expansion, we estab...