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Analysis of blood-based DNA methylation signatures of aging and disease progression in inflammatory bowel diseaseNARA Subscribed
Inflammatory bowel diseases (IBDs) are chronic inflammatory disorders influenced by environmental factors and characterised by a dysregulated immune response. DNA methylation (DNAm) a key epigenetic mechanism plays a role in the etiology of complex diseases like IBD. Epigenetic clocks which estimate biological aging through DNAm patterns have also been linked to various health states, including IBD. Previously, we profiled DNA...
Exploring relationships between oxygen consumption and biologger‐derived estimates of heart rate in two warmwater piscivoresNARA Subscribed
Estimating metabolic rate in wild, free‐swimming fish is inherently challenging. Here, we explored using surgically implanted heart rate biologgers to estimate metabolic rate in two warmwater piscivores, bowfin Amia calva (Linneaus 1766) and largemouth bass Micropterus salmoides (Lacepède 1802). Fish were surgically implanted with heart rate loggers, allowed to recover for 24 h, exposed to a netting and air exposure challenge,...
Motivation The BioTIME database contains raw data on species identities and abundances in ecological assemblages through time. These data enable users to calculate temporal trends in biodiversity within and amongst assemblages using a broad range of metrics. BioTIME is being developed as a community‐led open‐source database of biodiversity time series. Our goal is to accelerate and facilitate quantitative analysis of temporal...
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