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NARA Subscribed1
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Springer Nature1
Journal
Psychopharmacology1
Publication Year
20221
Trevor J. Bushell results 1 · Newest (Page 1/1, per page 25)
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Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokinesNARA Subscribed
Psychopharmacology · 2022 · Vol. 239 · Issue 1 · Springer
Serge Moudio; Ashleigh Willis; Karolina Pytka; Roua Abulkassim; Ros R. Brett; Jack F. Webster; Christian Wozny; Mark Barbour; Hui-Rong Jiang; David G. Watson; Josie C. van Kralingen; Scott M. MacKenzie; Michael Daniels; Barry W. McColl; Sandra Sossick; Hugh N. Nuthall; Trevor J. Bushell
Rationale Major depressive disorder (MDD) is a leading cause of disability worldwide but currently prescribed treatments do not adequately ameliorate the disorder in a significant portion of patients. Hence, a better appreciation of its aetiology may lead to the development of novel therapies. Objectives In the present study, we have built on our previous findings indicating a role for protease-activated receptor-2 (PAR2) in s...
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