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Molecular Neurobiology · 2024 · Vol. 61 · Issue 8 · Springer
Expansion of the GGGGCC-RNA repeat is a known cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), which currently have no cure. Recent studies have indicated the activation of Sigma-1 receptor plays an important role in providing neuroprotection, especially in ALS and Alzheimer’s disease. Nevertheless, the mechanisms underlying Sigma-1R activation and its effect on (G 4 C 2 )n-RNA-induced cell death...
Journal of Marine Science and Engineering · 2022 · Vol. 10 · Issue 9 · MDPI
Transient characteristics of wave generation in the wave channel can provide unique and important information in contrast to the steady and periodic motion of propagation waves. In this paper, a new analytical solution is proposed for a transient wavemaker problem in the wave channel. The mathematical model of the wavemaker problem is established based on the linear potential wave theory, and a new analytical solution for the...
Journal of Marine Science and Engineering · 2022 · Vol. 10 · Issue 6 · MDPI
In this study, the problem of surface waves induced by water flow in a flow channel was investigated. The mathematical model based on the potential wave theory was established, and a new analytic solution to the corresponding initial and boundary value problem was proposed. To confirm our analytic solution, the mathematical model was applied to simulate experiments conducted in a flow channel in the laboratory. Using our analy...
Journal of Molecular Medicine · 2021 · Vol. 99 · Issue 12 · Springer
Cognitive impairment is a serious side effect of post-myocardial infarction (MI) course. We have recently demonstrated that human adipose-derived stem cells (hADSCs) ameliorated myocardial injury after MI by attenuating reactive oxygen species (ROS) levels. Here, we studied whether the beneficial effects of intramyocardial hADSC transplantation can extend to the brain and how they may attenuate cognitive dysfunction via modula...
Purpose This paper presents our team’s results to establish an AIoT smart cage culture management system. Methods According to the built system, the farmed field information is transmitted to the data platform of Ocean Cloud, and all collected data and analysis results can be applied to the cage culture field after the bigdata analysis. Results This management system successfully integrates AI and IoT technologies and is appli...