NIMA-related kinase 2 (NEK2) is a serine/threonine kinase that plays crucial roles in cellular events such as centrosome separation, cell cycle progression, spindle assembly checkpoint (SAC) regulation, and microtubule stabilization. However, its regulatory function during oocyte meiotic maturation remains unclear. In this study, NEK2 activity was inhibited using the specific inhibitor MBM-55 to evaluate its role in oocyte mei...

Amnestic mild cognitive impairment represents a prodromal stage of Alzheimer’s disease characterized by episodic memory deficits and subtle alterations in brain function. Although the traditional herbal formula Kami Guibi-tang (KGT) has been reported to exert cognitive benefits, its neural effects have not been evaluated using functional neuroimaging. In this randomized, double-blind, placebo-controlled trial, 84 individuals w...