Recurrent pregnancy loss (RPL) is a multifactorial reproductive disease that is typified by repeated pregnancy loss with immune dysregulation emerging as a critical contributing factor. Immunoglobulins are among the immune components that are instrumental in preserving tolerance between the mother and the fetus, regulating inflammatory responses, and supporting placental development. This review provides a comprehensive overvi...

Acinetobacter baumannii is a Gram-negative opportunistic pathogen and a major cause of healthcare-associated infections, including ventilator-associated pneumonia, bacteraemia, meningitis, and urinary tract infections. Its persistence in hospital environments is due to its ability to survive desiccation, resist disinfectants, and colonize both biotic and abiotic surfaces. Virulence in A. baumannii is largely associated with st...

BCS class II candidates pose challenges in drug development due to their low solubility and permeability. Researchers have explored various techniques; co-amorphous and solid dispersion are major approaches to enhance in-vitro drug solubility and dissolution. However, in-vivo oral bioavailability remains challenging. Physiologically based pharmacokinetic (PBPK) modeling with a detailed understanding of drug absorption, distrib...