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A Replicable NeuroMark Template for Whole-Brain SPECT Reveals Data-Driven Perfusion Networks and Their Alterations in SchizophreniaNARA Subscribed
Single photon emission computed tomography (SPECT) is a highly specialized imaging modality that enables measurement of regional cerebral perfusion and, in particular, regional cerebral blood flow (rCBF). Recent technological advances have improved SPECT quantification and reliability, making it increasingly useful for studying rCBF abnormalities and perfusion–network alterations in psychiatric and neurological disorders. To c...
Effective Connectivity Identifies Divergent Cerebro-Cerebellar Network Organization in SchizophreniaNARA Subscribed
Introduction functional impairments in schizophrenia may arise from disruptions in large-scale brain networks. Emerging evidence highlights the cerebellum’s role in cognitive and affective regulations, yet its directional influence remains poorly understood. This study examines effective connectivity (EC) within cortico-striato-cerebellar networks in schizophrenia and healthy adults. Methods resting-state functional magnetic r...
ENIGMA + COINSTAC: Improving Findability, Accessibility, Interoperability, and Re-usabilityNARA Subscribed
The FAIR principles, as applied to clinical and neuroimaging data, reflect the goal of making research products F indable, A ccessible, I nteroperable, and R eusable. The use of the Collaborative Informatics and Neuroimaging Suite Toolkit for Anonymized Computation (COINSTAC) platform in the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) consortium combines the technological approach of decentralized analyses w...