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Peripheral microRNA signature in genetic frontotemporal dementia—findings from the GENFI initiativeNARA Subscribed
Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by significant clinical and genetic heterogeneity, with approximately 40% of cases linked to hereditary genetic mutations, including MAPT , GRN , and C9ORF72 . Recently, microRNAs (miRNAs) have emerged as key regulators of cellular processes related to neurodegeneration and as potential biomarkers for FTD. However, their relevance in presymptomatic stag...
Different temperature responses of mountain rockwalls, soils, and lakes to summer heat wavesNARA Subscribed
Mountain ecosystems are highly sensitive to climate variations. At fine spatial scales, high-elevation microclimates play a critical role in shaping biodiversity, hydrological processes, and ecosystem services, while also influencing the occurrence of natural hazards such as landslides, avalanches, and floods. Heat waves, which have been increasing in frequency and intensity due to global climate change, present significant ch...
Citizen science (also referred to as participatory science or community science), in which members of the general public contribute to scientific research, is not a new concept, as early examples of such studies can be found a couple of centuries ago. With the advancement of technology in an increasingly connected world, it has never been easier to engage citizen scientists in research projects. In this paper, we review citize...