Summary In this study, we compared the secondary metabolite profile of Fusarium fujikuroi and the histone deacetylase mutant Δ HDA1 . We identified a novel peak in Δ HDA1 , which was identified as beauvericin (BEA). Going in line with a 1000‐fold increased BEA production, the respective non‐ribosomal peptide synthetase (NRPS)‐encoding gene ( BEA1 ), as well as two adjacent genes ( BEA2 ‐ BEA3 ), were significantly up‐regulated...