Von Hippel-Lindau (VHL) disease is a hereditary tumor predisposition syndrome caused by pathogenic germline variants in the VHL gene. Patients with VHL disease have an increased risk of developing characteristic VHL disease-associated lesions such as clear cell renal cell carcinoma, retinal angioma, central nervous system hemangioblastoma, pancreatic neuroendocrine tumors and pheochromocytomas. Loss of the VHL gene results in...

Community-acquired pneumonia (CAP) is a major global health concern as it is a leading cause of morbidity, mortality and economic burden to the health care systems. In Germany, more than 15,000 people die every year from CAP. Climate change is altering weather patterns, and it may influence the probability and severity of CAP. The increasing frequency and intensity of extreme weather events necessitate the study of their impac...

The fundamental goal of a rare plant translocation is to create self‐sustaining populations with the evolutionary resilience to persist in the long term. Yet, most plant translocation syntheses focus on a few factors influencing short‐term benchmarks of success (e.g., survival and reproduction). Short‐term benchmarks can be misleading when trying to infer future growth and viability because the factors that promote establishme...

Understanding the immunogenetic basis of coronavirus (CoV) susceptibility in major pathogen reservoirs, such as bats, is central to inferring their zoonotic potential. Members of the cryptic Hipposideros bat species complex differ in CoV susceptibility, but the underlying mechanisms remain unclear. The genes of the major histocompatibility complex (MHC) are the best understood genetic basis of pathogen resistance, and differen...

Aim Our aim was to examine gracile capuchin ( Cebus ) and robust capuchin monkey ( Sapajus ) diversification, with a focus on recent Sapajus expansion within Amazonia. We wanted to reconstruct the biogeographical history of the clade using statistical methods that model lineages’ occupation of different regions over time in order to evaluate recently proposed ‘Out of Amazonia’ and ‘Reinvasion of Amazonia’ hypotheses as alterna...

Aim Capuchin monkey species are widely distributed across Central and South America. Morphological studies consistently divide the clade into robust and gracile forms, which show extensive sympatry in the Amazon Basin. We use genetic data to test whether Miocene or Plio‐Pleistocene processes may explain capuchin species’ present distributions, and consider three possible scenarios to explain widespread sympatry. Location The N...