This position paper was collaboratively written during the international expert symposium “EU Chemicals Assessment - Risk- or Hazard-based?” that was organised by the German Federal Institute for Risk Assessment (BfR) in Berlin on November 27th and 28th 2025. Twenty experts from several institutions and European countries considered the scientific merits of both hazard-based and risk-based approaches to chemical safety assessm...

The genus Dodonaea is thought to have originated from Australia but it is now found worldwide and in places where the plants occur, they hold ethnobotanical significance. This has prompted phytochemical and pharmacological studies. To date, secondary metabolite profiling has particularly focused on Dodonaea viscosa and such studies have shown that flavonoids and terpenoids are the dominant chemical constituents of this taxon....

Obesity and type 2 diabetes mellitus accelerate aging, shortening the duration of healthspan. Conversely, chronic calorie restriction (CR) extends healthspan. Research aimed at understanding the mechanism by which CR slows aging has focused heavily on insulin and downstream signaling cascades. Glucagon, a hormone that counter-regulates insulin, is commonly affected by these same interventions. To investigate the role of glucag...

Nearshore seagrass, kelp, and other macroalgae beds (submerged aquatic vegetation [SAV]) are productive and important ecosystems. Mitigating anthropogenic impacts on these habitats requires tools to quantify their ecological value and the debits and credits of impact and mitigation. To summarize and clarify the state of SAV habitat quantification and available tools, we searched peer‐reviewed literature and other agency docume...

Atoguanil™ is a novel complex of atovaquone (ATV) and proguanil (PG) with enhanced ATV bioavailability compared to Malarone®. This pilot study assessed whether the relative bioavailability (F rel ) of ATV, PG, and the primary PG metabolite cycloguanil (CG) following a single oral dose in the fed state of Atoguanil was similar to Malarone despite a 50% lower ATV dose. This open-label, single-dose, randomized 2-period, 2-treatme...

The occurrence of North Atlantic right whales ( Eubalaena glacialis ) in Cape Cod Bay was documented during aerial surveys between 1998 and 2013. The seasonal occurrence remained relatively unchanged during the study, spanning the January through mid‐May timeframe. The number of individual whales visiting the Bay was positively correlated with the increasing Best Cataloged Estimate (BCE), the number of photographed whales aliv...