Increasing evidence suggests that key cancer-causing driver genes continue to exert a sustained influence on the tumor microenvironment (TME), highlighting the importance of immunotherapeutic targeting of gene mutations in governing tumor progression. TP53 is a prominent tumor suppressor that encodes the p53 protein, which controls the initiation and progression of different tumor types. Wild-type p53 maintains cell homeostasi...

Factors shaping the interspecific variations in herbivory have puzzled ecologists for decades and several hypotheses have been proposed to explain interspecific variation in leaf herbivory. In a tropical rainforest in Yunnan Province, China, we collected 6732 leaves from 129 species with canopy heights ranging from 1.6 to 65.0 m above the ground. We tested the role of canopy height, the diversity, composition and structural he...

With the increasing maturity of underwater agents-related technologies, underwater object recognition algorithms based on underwater robots have become a current hotspot for academic and applied research. However, the existing underwater imaging conditions are poor, the images are blurry, and the underwater robot visual jitter and other factors lead to lower recognition precision and inaccurate positioning in underwater target...