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Atmospheric forcing and ocean preconditioning for dense shelf water cascading in the northwestern MediterraneanNARA Subscribed
Dense shelf water cascading (DSWC) in the northwestern Mediterranean Sea occurs due to the densification and overflow of shelf water in winter. This process ventilates the deep basin with waters that can be denser than those generated by open-ocean convection. Between 1987 and 2021 (i.e., 35 winter periods), shelf water reached depths greater than 1000 m on only 9 occasions, and open questions remain regarding the triggering f...
Cold‐water fishes, such as salmonids, face environmental stresses resulting from climate change. We examined the thermal acclimation response of the hatchery‐reared versus wild, native brook trout ( Salvelinus fontinalis ) to explore how the contractile properties and gene expression of their myotomal muscle might shift to mitigate the impact of a warming environment. Hatchery fish were acclimated to three temperatures (4, 10...
Seagrass meadows are key blue carbon (C) ecosystems, storing large amounts of organic C over centuries. Their climate benefits may be reduced by methane (CH 4 ) emissions, whose microbial and environmental descriptors in Zostera noltii meadows, dominant seagrass in North‐Western Europe, remain poorly understood. We studied CH 4 fluxes, CH 4 ‐producing and consuming microbial communities and sediment physicochemical parameters...
Structure–activity relationship of synthetic cathinones: integrated in silico, in vitro, and in vivo studies of α-PiHP analoguesNARA Subscribed
Synthetic cathinones represent the main group of emerging psychostimulants consumed worldwide. Structural modifications of these compounds have led to pyrovalerones, potent dopamine transporter (DAT) inhibitors associated with high abuse liability. Among them, α-pyrrolidinoisohexanophenone (α-PiHP) became the most seized pyrovalerone in the European Union in 2023. Novel analogues have rapidly appeared, yet their neuropharmacol...
Human‐induced high densities of large wild herbivores may pose a threat to natural ecosystems, modifying biodiversity and ecosystem functioning. Although the negative impacts on individual taxa and processes are well documented, a comprehensive understanding of how ecosystem integrity responds to high herbivore densities remains limited. This study addresses this gap through an extensive herbivore‐density manipulation experime...
Prioritizing bat roosts for conservation with a global multicriteria bat roost priority index based on community scienceNARA Subscribed
Prioritization in conservation is crucial for the development of efficient and effective decision‐making policies. For many decades, the importance of some species and their habitats has been assessed and applied in conservation legislation, but bats and their diurnal roosts have ofbeen overlooked. Several approaches have been used to categorize bat roosts based on their conservation importance. However, such assessments are o...
The impact of the 2024 coral bleaching event on corals at a remote atoll in the Tuamotu Archipelago, French PolynesiaNARA Subscribed
Coral reefs are under severe threat from global warming, particularly due to the increasing frequency of mass coral bleaching events. This study documents the effects of the fourth global coral bleaching event on corals of Tahanea, a remote uninhabited French Polynesian atoll over a 10-month period. Coral surveys (transects and tracking of individual colonies) and temperature monitoring were conducted by one in situ observer....
Integration of Multi-Omics Data To Understand the Multifaceted Role of RAMP1 across Different Cancer TypesNARA Subscribed
Receptor Activity-Modifying Protein 1 (RAMP1) is a Calcitonin Receptor-Like Receptor (CALCRL)-associated protein with significant relevance in oncogenesis and tumor progression. It acts as a context-dependent allosteric modulator of GPCRs. This integrative review synthesizes evidence from multiple omics layers—transcriptomics, proteomics, epigenomics, and pan-cancer datasets—to clarify the role of RAMP1, its signaling pathways...