Tidal flats are shrinking and eroding due to sea-level rise and human activities. Ecological submerged breakwaters (ESBs) offer a novel solution combining coastal protection and ecological restoration, but their effects on sediment dynamics lack field evidence. This study presents synchronous in situ measurements from an inner tidal flat (WN01) and an outer shallow area (WN02) of a newly built riprap slope-type ESB on the nort...

Under the combined pressures of natural variability and human activities, the area of tidal flats has been gradually decreasing, with most muddy coasts experiencing varying degrees of erosion. The central coast of Jiangsu Province, a world-renowned region for extensive tidal flats, has witnessed intensifying erosion of its muddy coasts in recent years. To mitigate further coastal erosion, an ecological submerged breakwater (ES...

In deep-sea oil and gas development scenarios, deep-sea dual-channel connectors often face the risk of seal failure due to internal and external temperature difference loads. To address this issue, this paper systematically establishes equivalent heat transfer models for the key parts of the connector based on the third-type boundary condition. On this basis, the quantitative correlation between the equivalent thermal conducti...

Mycophenolic acid (MPA), the active moiety of both mycophenolate mofetil (MMF) and enteric-coated mycophenolate sodium (EC-MPS), serves as a primary immunosuppressant for maintaining solid organ transplants. Therapeutic drug monitoring (TDM) enhances treatment outcomes through tailored approaches. This study aimed to develop an evidence-based guideline for MPA TDM, facilitating its rational application in clinical settings. Th...