Xu-Rui Hu results 245
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Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weightNARA Subscribed
An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the underlying genetic mechanism remains unclear. Here, we applied a pleiotropic conditional false discovery rate (cFDR) approach to the genome-wide association study (GWAS) summary statistics for lumbar spine bone mineral density (LS BMD) and BW, aiming to identify novel susceptibil...
QsvR integrates into quorum sensing circuit to control Vibrio parahaemolyticus virulenceNARA Subscribed
Summary Vibrio parahaemolyticus , the leading cause of seafood‐associated gastroenteritis worldwide, requires the two type‐III secretion systems (T3SS1 and T3SS2) and a thermostable direct hemolysin (encoded by tdh1 and tdh2 ) for full virulence. The tdh genes and the T3SS2 gene cluster constitute an 80 kb pathogenicity island known as Vp‐PAI located on the chromosome II. Expression of T3SS1 and Vp‐PAI is regulated in a quorum...