Lung adenocarcinoma (LUAD), characterized by its complex molecular heterogeneity and resistance to both conventional and targeted therapies, poses significant therapeutic challenges. Therefore, the identification of novel molecular targets is crucial for enhancing therapeutic strategies and improving patient outcomes. This study investigates the role of mitochondrial ribosomal protein S17 (MRPS17) in the progression of LUAD, w...

With the escalation of global warming, the potential for land evaporation in the Yellow River Basin (YRB) has increased remarkably, and the problem of soil drought has become increasingly prominent. This not only restricts the development of the agricultural economy in the basin, but also intensifies the disparity between water availability and demand, and exerts a profound influence on the ecological security of the basin. In...

Maritime transport faces increasing “double random” risks—simultaneous supply disruptions and stochastic demand fluctuations. This study investigates the effectiveness of backup supply strategies in mitigating such risks, using crude oil procurement via the Strait of Hormuz as a case study. We develop a stochastic optimization model comparing two procurement scenarios: sole reliance on a primary supplier versus inclusion of a...