Yanping Ni results 19
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The regulatory gene wblA is a target of the orphan response regulator OrrA in Streptomyces coelicolorNARA Subscribed
Summary Our previous study using transposon mutagenesis indicated that disruption of the putative response regulator gene orrA impacted antibiotic production in Streptomyces coelicolor . In this study, the role of OrrA was further characterized by comparing the phenotypes and transcriptomic profiles of the wild‐type S . coelicolor strain M145 and Δ orrA , a strain with an inactivated orrA gene. Chromatin immunoprecipitation us...
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