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Environmental Microbiology · 2022 · Vol. 24 · Issue 7 · Wiley
Summary Our previous study using transposon mutagenesis indicated that disruption of the putative response regulator gene orrA impacted antibiotic production in Streptomyces coelicolor . In this study, the role of OrrA was further characterized by comparing the phenotypes and transcriptomic profiles of the wild‐type S . coelicolor strain M145 and Δ orrA , a strain with an inactivated orrA gene. Chromatin immunoprecipitation us...