The inflammasome is a multimeric protein complex located in the cytoplasm that is activated by many factors and subsequently promotes the release of proinflammatory factors such as interleukin (IL)-1β and IL-18, resulting in a series of inflammatory responses that ultimately lead to the occurrence of various diseases. The Nod-like receptor protein 3 (NLRP3) inflammasome is the most characteristic type and the most widely studi...

Summary The formation of sexual fruiting bodies and production of polyketides are believed to be the most important strategies for fungal survival in environmental insults. In Neurospora crassa , the backbone gene of polyketide synthase gene cluster 6 (pks‐6 ), which is expressed at lower level under vegetative growth, is highly expressed during perithecia development. Intriguingly, deletion of pks‐6 does not affect perithecia...