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As the world's population grows, aquaculture is becoming a rapidly growing source of protein. Grass carp ( Ctenopharyngodon idella ) is one of the most important aquacultured species in China and has emerged as a significant commercial fish worldwide. However, grass carp reovirus (GCRV) poses a significant threat to grass carp aquaculture. This review covers GCRV biology, phylogeny, pathogenesis, immune response pathways, ther...
A Survey of the Species Origins of Common Fish Cell Lines—With a Particular Focus on the Grass Carp Ovarian Cell Line ( GCO )NARA Subscribed
Cell line misidentification or contamination undermines the reliability of research outcomes. In this study, we verified the species origin of commonly used fish cell lines, with a particular focus on the grass carp ovarian cell line (GCO). RNA‐seq data from 146 samples of 11 widely used fish cell lines were collected from public databases (NCBI‐SRA) and were mapped to the reference genomes of eight species. GCO RNA‐seq sample...
SNCA is a potential therapeutic target for COVID-19 infection in diffuse large B-cell lymphoma patientsNARA Subscribed
Cuprotosis related genes (CRGs) have been proved to be potential therapeutic targets for coronavirus disease 2019 (COVID-19) and cancer, but their immune and molecular mechanisms in COVID-19 infection in Diffuse Large B-cell Lymphoma (DLBC/DLBCL) patients are rarely reported. Our research goal is first to screen the key CRGs in COVID-19 through univariate analysis, machine learning and clinical samples. Secondly, we determined...
As a member of the pattern recognition receptor (PRR) class, scavenger receptor class B type 1 (SRB1) plays a key role in innate immunity. Grass carp (Ctenopharyngodon idellus) ranks among the most extensively cultivated freshwater aquaculture species in China. However, little is known about the function of SRB1 in C. idellus. In this research study, a SRB1 gene was identified in C. idellus, named CiSRB1. The full-length cDNA...
Sediment resuspension and transport in the offshore subaqueous Yangtze Delta during winter stormsOA Marine
Storm-induced episodic sediment redistribution in coastal systems can reshape geomorphic bodies, disrupt ecosystems, and cause economic damage. However, cold-wave-storm-induced hydrodynamic changes and residual sediment transport in large, exposed subaqueous deltas, such as the Yangtze Delta, are poorly understood because it is typically expensive and difficult to obtain systematic field data in open coast settings during stor...