In the context of global climate change, intensified salinity fluctuations driven by altered precipitation, extreme rainfall events, and typhoons have emerged as a major threat to coastal mollusk aquaculture. In this study, integrated physiological and transcriptomic analyses were performed to investigate the responses of Pacific abalone (DD, Haliotis discus hannai) and its hybrid (DF, H. discus hannai ♀ × H. fulgens ♂) to hyp...