Yi D. Lin results 41
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PROMETHEUS clinical trial protocol: tailoring healthy ageing with lifestyle and nutraceuticalsNARA Subscribed
The d emographic shift toward an older population is accelerating the prevalence of age-related diseases. Precision geromedicine represents a paradigm shift in targeting the biological processes of ageing to optimise health and healthspan, which likely requires multimodal tailored interventions. PROMETHEUS, as part of the XPRIZE healthspan semi-finalist competition, is an 8-week feasibility and exploratory study including 20 m...
Precision measurement of the Ds*+-Ds+ meson mass differenceNARA Subscribed
Sepsis survivors frequently experience post-discharge physical function decline and encounter logistical barriers to participation in traditional outpatient rehabilitation. This pilot study examined the feasibility, safety, and preliminary efficacy of a remotely delivered, home-based exercise program on physical function in older sepsis survivors. In this single-blinded, randomized controlled trial (RCT), sepsis survivors aged...
Introduction The myodural bridge (MDB) is considered one of the circulatory dynamics of cerebrospinal fluid (CSF). Initially identified in the human neck, it has since been documented across diverse vertebrates, including fish with analogous “MDB-like” structures. The teleost Takifugu rubripes , which exhibits a high degree of genetic homology with humans, serves as an excellent model for such comparative studies. Investigatin...
Nicotinamide riboside combined with exercise to treat hypertension in middle-aged and older adults: a pilot randomized clinical trialNARA Subscribed
Aerobic exercise lowers blood pressure (BP) with varying effects in hypertensive adults, potentially due to age-related nicotinamide adenine dinucleotide (NAD) metabolism dysregulation. This pilot randomized clinical trial (RCT) tested the efficacy of combining aerobic exercise with the NAD booster nicotinamide riboside (NR) to enhance BP control. In this double-blinded RCT, 54 sedentary adults (≥ 55 years) with mean daytime s...
Although Southeast Asia is a hotspot of global seagrass diversity, there are considerable information gaps in the distribution of seagrass beds. Broad-scale seagrass distribution has not been updated in the global seagrass database by UNEP-WCMC since 2000, although studies on seagrasses have been undertaken intensively in each region. Here we analyze the recent distribution of tropical seagrass beds, their temporal changes, ca...
Taxonomy of the order Mononegavirales: second update 2018NARA Subscribed