Cynoglossus semilaevis parvovirus (CsPV) is an important pathogen that poses a serious threat to the aquaculture industry. In the absence of vaccines and effective therapeutic drugs, early and sensitive detection of the pathogen is the key measure to prevent and control the outbreaks and epidemics of viral diseases. Currently, the existing detection methods for CsPV are expensive and rely on specialized operations, limiting th...

Submarine channels are critical conduits for sediment transport by turbidity currents, yet the quantitative influence of channel geometry on flow dynamics and sediment segregation remains poorly understood. Based on computational fluid dynamics, we constructed six three-dimensional numerical models of submarine channels with varying curvatures (R1–R3) and axial slopes (R4–R6) using ANSYS Fluent 17.2, with model settings inform...

Ischemic cerebrovascular disease involves complex interactions between metabolic reprogramming and epigenetic regulation. Recent studies indicate that enhanced glycolysis and lactate accumulation under hypoxic conditions not only maintain cell viability by supplying energy but also participate in disease regulation through lactylation. Lactylation regulates gene expression, immune polarization, metabolic enzyme activity, and a...