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Inflammation Research · 2023 · Vol. 72 · Issue 8 · Springer
Objective We aimed to reveal a spatial proteomic and immune signature of kidney function regions in lupus nephritis (LN). Material and methods The laser capture microdissection (LCM) was used to isolate the glomerulus, tubules, and interstitial of the kidney from paraffin samples. The data-independent acquisition (DIA) method was used to collect proteomics data. The bioinformatic analysis was performed. Results A total of 49,6...