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Deep Immunophenotyping Unravels the Double Negative T cells and PD-1-Mediated Inflammatory Exhaustion in Ankylosing SpondylitisNARA Subscribed
Ankylosing spondylitis (AS) is a chronic, immune-mediated inflammatory disorder primarily affecting the axial skeleton. It is characterized by bony fusion and syndesmophyte formation of the spine, leading to compromised mobility, reduced quality of life and increased mortality. However, the underlying immune dysregulation in AS remains poorly understood. We comprehensively profiled the peripheral immune landscape of 30 patient...
Background Soil moisture is a key variable in precision agriculture, affecting irrigation management, crop productivity, and water-use efficiency. However, field-scale soil moisture monitoring remains challenging because conventional sensing approaches are often costly and provide limited spatial coverage. This study proposes a simulation-based framework for soil moisture mapping that integrates near-ground radio-frequency (RF...