Immunogenic cell death (ICD) can activate immune cells and potentiate the response to immunotherapy. The mitogen-activated protein kinase (MAPK) signaling pathway regulates the immune response and mediates T-cell receptor signaling. Activation of the MAPK signaling pathway decreases the levels of tumor-infiltrating lymphocytes in triple-negative breast cancer (TNBC) and is associated with worse survival. Here, we investigated...

Farming models profoundly influence the biological traits of aquatic organisms. This study compared muscle nutrients, muscle transcriptome, and gut microbiota of Pelodiscus sinensis reared under rice-field and pond conditions. Compared with the pond group (Group P), the rice-field group (Group R) exhibited significantly lower linoleic acid (LA) and higher arachidonic acid (ARA), indicating an altered muscle fatty acid profile....