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Interplay between Nrf2 and ROS in regulating epithelial-mesenchymal transition: implications for cancer metastasis and therapyNARA Subscribed
Epithelial-mesenchymal transition (EMT), including developmental (Type I), wound healing (Type II), and pathological (Type III) subtypes, constitutes a critical driver of cancer metastasis. This review analyzes the redox interplay between nuclear factor erythroid 2-related factor 2 (Nrf2) and reactive oxygen species (ROS) in EMT regulation and cancer progression. Nrf2 maintains redox homeostasis through antioxidant gene activa...
Healthy Yellow River carp (Cyprinus carpio haematopterus) reared at a water temperature of 23 ± 0.6 °C were orally administered albendazole (ABZ) at a dose of 12 mg/kg body weight (BW) once daily for seven consecutive days. At predetermined time points after the final administration, five fish were randomly selected for sampling. Plasma, skin-on-muscle, liver, and kidney tissues were collected, and the concentrations of ABZ an...