Yu-Rui Li results 30
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Using 2D/3D seismic data and a large number of drilling and logging data and applying sequence stratigraphy, seismic sedimentology, and petroleum geology concepts, the characteristics of the sedimentary sequence of the forced regression have been analysed, the migration trajectory of the coastline have been reconstructed, the evolution model of the forced regression have been presented, and the significance for petroleum geolo...
Chronic Exposure to Hypoxia Inhibits Myelinogenesis and Causes Motor Coordination Deficits in Adult MiceNARA Subscribed
Exposure to chronic hypoxia is considered to be a risk factor for deficits in brain function in adults, but the underlying mechanisms remain largely unknown. Since active myelinogenesis persists in the adult central nervous system, here we aimed to investigate the impact of chronic hypoxia on myelination and the related functional consequences in adult mice. Using a transgenic approach to label newly-generated myelin sheaths (...
Dicer Deletion in Astrocytes Inhibits Oligodendroglial Differentiation and MyelinationNARA Subscribed
Increasing evidence has shown that astrocytes are implicated in regulating oligodendrocyte myelination, but the underlying mechanisms remain largely unknown. To understand whether microRNAs in astrocytes function in regulating oligodendroglial differentiation and myelination in the developing and adult CNS, we generated inducible astrocyte-specific Dicer conditional knockout mice (hGFAP-CreERT; Dicer fl/fl). By using a reporte...
Aim The Sino‐Japanese Floristic Region has extremely high species diversity with respect to temperate plants; however, the reasons for this diversity are poorly understood because most studies have only considered geographic isolation caused by climatic oscillations. In some plant groups, high floral trait diversity and uneven species diversity between insular systems and the continental area suggest other factors may have imp...
Antifungal Effect of Long Noncoding RNA 9708-1 in the Vulvovaginal Candidiasis Murine ModelNARA Subscribed
Vulvovaginal candidiasis (VVC) caused by Candida spp. affects 70–75% of women at least once during their lives. We aim to elucidate the potential mechanism of VVC and investigate the therapeutic effects of long noncoding RNA 9708-1. Female BALB/c mice were randomized to four treatment groups, including the blank control group, VVC control group, vehicle control group and lncRNA 9708-1-overexpressed group. Mice were euthanized...