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microRNA (miRNA) is a type of endogenous short-chain non-coding RNA with regulatory function found in eukaryotes, which is involved in the regulation of a variety of cellular and biological processes. However, the research on the development of cashmere goat secondary hair follicles is still relatively scarce. In this study, small RNA libraries and mRNA libraries of 45 days, 55 days, 65 days, and 75 days of fetal skin of cashm...
Clinical profiles and antimicrobial resistance patterns of invasive Salmonella infections in children in ChinaNARA Subscribed
Invasive Salmonella infections result in a significant burden of disease including morbidity, mortality, and financial cost in many countries. Besides typhoid fever, the clinical impact of non-typhoid Salmonella infections is increasingly recognized with the improvement of laboratory detection capacity and techniques. A retrospective multicenter study was conducted to analyze the clinical profiles and antimicrobial resistance...
The Kuroshio Extension (KE) region is one of the most energetic regions in the global ocean where prominent mesoscale dynamics persistently occur. The spatial distribution and temporal evolution of the sea surface temperature (SST) gradient and mesoscale eddies in the KE are investigated. The SST gradient can be applied for identifying the fronts, and the SST gradient within two times the radii of the eddies is composited to q...
Coastal aquifers play key roles in providing freshwater resources to maintain the social and economic development in coastal areas. However, climate change and human activities have dramatically affected the quantities and qualities of groundwater in coastal aquifers. In this study, stoichiometric analysis of hydrogeochemistry, multivariate analysis, and isotopic trancing techniques were used to reveal the local hydrochemistry...
Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weightNARA Subscribed
An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the underlying genetic mechanism remains unclear. Here, we applied a pleiotropic conditional false discovery rate (cFDR) approach to the genome-wide association study (GWAS) summary statistics for lumbar spine bone mineral density (LS BMD) and BW, aiming to identify novel susceptibil...