Intracerebral hemorrhage (ICH) is a life-threatening cerebrovascular disorder frequently accompanied by blood–brain barrier (BBB) disruption. Endothelial apoptosis is a key contributor to BBB damage, leading to loss of barrier function, exacerbation of brain edema and inflammation, and a cascade of adverse outcomes. Previous studies have shown that extracellular vesicles (EVs) released from M2-polarized microglia are enriched...

An accurate model plays an important role in control strategy development of smart ships. For the control-oriented engine models, calibration by experienced personnel is key to outputting high accuracy. However, the dual-fuel engine runs in liquid fuel mode, gas fuel mode, and fuel sharing mode. It is impossible to tune a single model or a set of parameters for the dual-fuel engine under all operating modes and loads. On the b...

Oryza punctata , a wild relative of cultivated rice, belongs to the BB genome of Oryza . Interspecific hybrids (CW008, AB) between Oryza sativa (2 n = 24 AA) and O . punctata (2 n = 24 BB) were obtained using embryo rescue technique. Synthetic allopolyploid (DCW008, AABB) were produced through chromosome doubling by colchicine. Hybrids overcame many wild traits except the shattering and awn. The synthetic amphiploid plants sho...