The intensification of aquaculture and global climate change expose aquatic animals to multifaceted environmental stressors, triggering diverse stress‐response cascades to mitigate cellular damage and preserve physiological homeostasis. Autophagy, an evolutionarily conserved lysosome‐dependent catabolic process that degrades damaged or redundant cellular components to maintain cellular homeostasis and physiological functions,...

Functioning as a master coordinator, the mechanistic target of rapamycin (mTOR) coordinates nutrient availability and energy status to fundamental biological processes including growth, metabolism, and physiological homeostasis through evolutionarily conserved mechanisms. The capacity of mTOR to assimilate nutritional and metabolic signals places it as a central focus in aquaculture nutrition research. This review systematical...