Platinum-based chemotherapeutic agents constitute the cornerstone of treatment for a wide range of solid tumors. However, residual platinum can persist in the body long after treatment cessation, leading to progressive accumulation, chronic multi-system toxicity, and significant impairment of patients' quality of life. The insidious onset and lack of specific monitoring methods often lead to the oversight of this treatment-rel...

Permafrost forests harbor vast, climate‐sensitive carbon (C) reservoirs whose vulnerability largely depends on temperature sensitivity of microbial respiration ( Q 10 ). However, substantial uncertainties persist in predicting Q 10 patterns due to complex interactions among multiple ecological factors. Here, we conducted a standardized field survey with controlled incubations across a regional gradient from continuous permafro...

Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic...