Antisense oligonucleotide (ASO) is a novel therapeutic platform for targeted cancer therapy. Previously, we have demonstrated that miR-146b-5p plays an important role in colorectal cancer progression. However, a safe and effective strategy for delivery of an ASO to its targeted RNA remains as a major hurdle in translational advances. Human umbilical cord mesenchymal cell (hUC-MSC)–derived exosomes were used as vehicles to deli...

Under global warming, the frequent occurrence of Eurasian extreme cold events in the Northern Hemisphere in recent years has attracted widespread attention. Winter Eurasia near‐surface anticyclone activities are closely related to low temperatures. This study uses a new objective anticyclone identification algorithm based on a Mask region‐based convolutional neural network (Mask R‐CNN) to detect long‐term winter Eurasian antic...